I have excel spreadsheet
I am looking to know date-time when my excel cells have been modified last time.
Can I do it in Excel or Access?
If yes, what function I can use?
in Excel, you can Track Changes
This opens up the workbook for sharing, and you can even tell Excel to track specific cells, and if you want your changes tracked or not.
This is an example of what you see when values are changed:
You can use this Track Changes feature to find out the last modifier date of a cell and find who the user was.
How to Track Changes in Excel 2007