Link From excel to open pdf file

You can link the PDF file with Insert > Hyperlink > [path of file] When the link is clicked and the PDF file exists at that location on the machine, the file will be opened (after the accepts it in a warning dialog).

I strongly doubt though, that it is at all possible, to link to a specific page in a PDF. But why not just specify the relevant page in a note next to the link.

Example:

Further Details, see the Documentation:
D:\Documents\Docs\Documentation.pdf
(Page 21)

You can write a macros to start Acrobat with parameters.

When opening a PDF document from a command shell, you can pass the parameters to the open
command using the /A switch with the following syntax:

<Acrobat path> /A "<parameter>=<value>" "<PDF path>"
For example:
Acrobat.exe /A "page=8" "C:\example.pdf"

link

A working implementation of the VBA suggestion from Andrii Horda would be…

(With Acrobat Reader DC and the links to the PDF files listed in Column E)

Sub Worksheet_SelectionChange(ByVal Target As Range)
Row = Target.Row
Column= "E"
Path= Range(Column & Row)
If Target.Column = "5" Then
Shell """" & Environ("ProgramFiles") & "\Adobe\Acrobat Reader 2015\Reader\AcroRd32.exe"" /A ""page=2"" """ & Path & """", vbNormalFocus
End If
End Sub